Cardiac autonomic function during sleep of never-depressed borderline subjects: A pilot study

Marco Battaglia, Luigi Ferini-Strambi, Salvatore Smirne, Luana Bernardeschi, Alessandro Oldani, Laura Bellodi

Research output: Contribution to journalArticlepeer-review

Abstract

In a controlled 48 h ambulatory polysomnographic study of never-depressed subjects with DSM-III-R borderline (BDL) personality disorder (PD) we obtained measures of tonic and phasic heart rate variability. Subjects with BDL PD showed a significantly smaller index of tonic heart rate decrease during NREM sleep than normal controls. This is unlikely to be a state-dependent finding and it may derive from relative augmentation of adrenergic function compared to cholinergic function between wakefulness and NREM sleep. Hyperadrenergic states in BDL PD have already been suggested by studies of other biological indicators: a smaller index of tonic heart rate decrease may be a further correlate of core psychobiological dimensions such as impulsivity and affective instability.

Original languageEnglish
Pages (from-to)397-405
Number of pages9
JournalJournal of Psychiatric Research
Volume29
Issue number5
Publication statusPublished - Sep 1995

ASJC Scopus subject areas

  • Biological Psychiatry
  • Psychiatry and Mental health
  • Psychology(all)

Fingerprint Dive into the research topics of 'Cardiac autonomic function during sleep of never-depressed borderline subjects: A pilot study'. Together they form a unique fingerprint.

Cite this