Abstract
ECGs and left ventricular systolic time intervals were studied in 26 patients suffering from major depressive disorder treated with clomipramine. ECGs did not show, with one exception, drug-induced changes. The ratio of pre-ejection period to left ventricular ejection time, both corrected for heart rate (PEPc/LVETc), presented no significant changes, as compared with initial findings, in the group of patients considered as a whole. 27 % of patients, however, showed individual percent changes greater than 8 %, both increases and decreases having been observed. Cardiac findings were in no way related to clomipramine plasma levels.
| Original language | English |
|---|---|
| Pages (from-to) | 113-118 |
| Number of pages | 6 |
| Journal | Neuropsychobiology |
| Volume | 9 |
| Issue number | 2-3 |
| DOIs | |
| Publication status | Published - 1983 |
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Keywords
- Clomipramine
- Drug-induced blocks and cardiac arrhythmias
- ECG
- Systolic time intervals (STI)
ASJC Scopus subject areas
- Psychiatry and Mental health
- Biological Psychiatry
- Neuropsychology and Physiological Psychology
- Neuroscience(all)
- Psychology(all)
Cite this
Cardiac effects of clomipramine treatment : ECG and left ventricular systolic time intervals. / Farovelli, C.; Brat, A.; Marchetti, G.; Franchi, F.; Padeletti, L.; Michelucci, A.; Pastorino, A.
In: Neuropsychobiology, Vol. 9, No. 2-3, 1983, p. 113-118.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Cardiac effects of clomipramine treatment
T2 - ECG and left ventricular systolic time intervals
AU - Farovelli, C.
AU - Brat, A.
AU - Marchetti, G.
AU - Franchi, F.
AU - Padeletti, L.
AU - Michelucci, A.
AU - Pastorino, A.
PY - 1983
Y1 - 1983
N2 - ECGs and left ventricular systolic time intervals were studied in 26 patients suffering from major depressive disorder treated with clomipramine. ECGs did not show, with one exception, drug-induced changes. The ratio of pre-ejection period to left ventricular ejection time, both corrected for heart rate (PEPc/LVETc), presented no significant changes, as compared with initial findings, in the group of patients considered as a whole. 27 % of patients, however, showed individual percent changes greater than 8 %, both increases and decreases having been observed. Cardiac findings were in no way related to clomipramine plasma levels.
AB - ECGs and left ventricular systolic time intervals were studied in 26 patients suffering from major depressive disorder treated with clomipramine. ECGs did not show, with one exception, drug-induced changes. The ratio of pre-ejection period to left ventricular ejection time, both corrected for heart rate (PEPc/LVETc), presented no significant changes, as compared with initial findings, in the group of patients considered as a whole. 27 % of patients, however, showed individual percent changes greater than 8 %, both increases and decreases having been observed. Cardiac findings were in no way related to clomipramine plasma levels.
KW - Clomipramine
KW - Drug-induced blocks and cardiac arrhythmias
KW - ECG
KW - Systolic time intervals (STI)
UR - http://www.scopus.com/inward/record.url?scp=0020507847&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0020507847&partnerID=8YFLogxK
U2 - 10.1159/000117948
DO - 10.1159/000117948
M3 - Article
C2 - 6621851
AN - SCOPUS:0020507847
VL - 9
SP - 113
EP - 118
JO - Neuropsychobiology
JF - Neuropsychobiology
SN - 0302-282X
IS - 2-3
ER -