Cardiac magnetic resonance 'virtual catheterization' for the quantification of valvular regurgitations and cardiac shunt

Giovanni D onato Aquaro, Andrea Barison, Giancarlo Todiere, Pierluigi Festa, Lamia Ait-Ali, Massimo Lombardi, Gianluca Di Bella

Research output: Contribution to journalArticlepeer-review

Abstract

Cardiac magnetic resonance (CMR) is considered the gold-standard noninvasive technique for the quantification of ventricular volumes by cine-imaging and of vascular flows by velocity-encoded phase contrast (VENC). In routine CMR scans, it is common to found clinical conditions, as valve regurgitations and cardiac shunts, producing a volume overload and significant mismatch between the right and left ventricular stroke volumes (RSV and LSV). In the presence of a valve regurgitation, the volume overload involves the respective ventricular chamber, whereas in cardiac shunts, the location of the volume overload depends on the site of the anatomic defect. Moreover, when a cardiac shunt is present, pulmonary and systemic cardiac outputs are different (Qp/Qs  1), whereas in the presence of valve regurgitation, Qp/Qs = 1. Therefore, by combining the cine-imaging with the VENC technique, it is possible to investigate the cardiac physiology underlying different pathological conditions producing volume overload, and to quantify this overload (the regurgitant volume and/or shunt volume). In this report, we discussed the technical, theoretical and methodological aspects of this sort of 'virtual catheterization' by CMR, providing a simple algorithm to make the correct diagnosis.

Original languageEnglish
Pages (from-to)663-670
Number of pages8
JournalJournal of Cardiovascular Medicine
Volume16
Issue number10
DOIs
Publication statusPublished - Oct 1 2015

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of 'Cardiac magnetic resonance 'virtual catheterization' for the quantification of valvular regurgitations and cardiac shunt'. Together they form a unique fingerprint.

Cite this