TY - JOUR
T1 - Cardiac magnetic resonance 'virtual catheterization' for the quantification of valvular regurgitations and cardiac shunt
AU - Aquaro, Giovanni D onato
AU - Barison, Andrea
AU - Todiere, Giancarlo
AU - Festa, Pierluigi
AU - Ait-Ali, Lamia
AU - Lombardi, Massimo
AU - Di Bella, Gianluca
PY - 2015/10/1
Y1 - 2015/10/1
N2 - Cardiac magnetic resonance (CMR) is considered the gold-standard noninvasive technique for the quantification of ventricular volumes by cine-imaging and of vascular flows by velocity-encoded phase contrast (VENC). In routine CMR scans, it is common to found clinical conditions, as valve regurgitations and cardiac shunts, producing a volume overload and significant mismatch between the right and left ventricular stroke volumes (RSV and LSV). In the presence of a valve regurgitation, the volume overload involves the respective ventricular chamber, whereas in cardiac shunts, the location of the volume overload depends on the site of the anatomic defect. Moreover, when a cardiac shunt is present, pulmonary and systemic cardiac outputs are different (Qp/Qs 1), whereas in the presence of valve regurgitation, Qp/Qs = 1. Therefore, by combining the cine-imaging with the VENC technique, it is possible to investigate the cardiac physiology underlying different pathological conditions producing volume overload, and to quantify this overload (the regurgitant volume and/or shunt volume). In this report, we discussed the technical, theoretical and methodological aspects of this sort of 'virtual catheterization' by CMR, providing a simple algorithm to make the correct diagnosis.
AB - Cardiac magnetic resonance (CMR) is considered the gold-standard noninvasive technique for the quantification of ventricular volumes by cine-imaging and of vascular flows by velocity-encoded phase contrast (VENC). In routine CMR scans, it is common to found clinical conditions, as valve regurgitations and cardiac shunts, producing a volume overload and significant mismatch between the right and left ventricular stroke volumes (RSV and LSV). In the presence of a valve regurgitation, the volume overload involves the respective ventricular chamber, whereas in cardiac shunts, the location of the volume overload depends on the site of the anatomic defect. Moreover, when a cardiac shunt is present, pulmonary and systemic cardiac outputs are different (Qp/Qs 1), whereas in the presence of valve regurgitation, Qp/Qs = 1. Therefore, by combining the cine-imaging with the VENC technique, it is possible to investigate the cardiac physiology underlying different pathological conditions producing volume overload, and to quantify this overload (the regurgitant volume and/or shunt volume). In this report, we discussed the technical, theoretical and methodological aspects of this sort of 'virtual catheterization' by CMR, providing a simple algorithm to make the correct diagnosis.
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U2 - 10.2459/JCM.0000000000000245
DO - 10.2459/JCM.0000000000000245
M3 - Article
C2 - 25643193
AN - SCOPUS:84973432149
VL - 16
SP - 663
EP - 670
JO - Journal of Cardiovascular Medicine
JF - Journal of Cardiovascular Medicine
SN - 1558-2027
IS - 10
ER -