Cardiomyopathy and multicore myopathy with accumulation of intermediate filaments

E. Bertini, C. Bosman, M. Bevilacqua, E. Ricci, G. M. Gagliardi, F. Parisi, S. Servidei, C. Dionisi-Vici, L. Ballerini

Research output: Contribution to journalArticlepeer-review

Abstract

A girl affected by a restrictive cardiomyopathy with neuromuscular involvement is described. Morphological examination showed a pattern of multicore myopathy and with electron microscopy a sarcoplasmic accumulation of electron dense granular and filamentous material was demonstrated both in skeletal muscle and heart. This peculiar electron dense material corresponded to increased desmin in muscle and cardiac fibres and was demonstrated immunohistochemically.

Original languageEnglish
Pages (from-to)856-858
Number of pages3
JournalEuropean Journal of Pediatrics
Volume149
Issue number12
DOIs
Publication statusPublished - Sep 1990

Keywords

  • Desmin accumulation
  • Multicore myopathy
  • Restrictive cardiomyopathy

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Fingerprint Dive into the research topics of 'Cardiomyopathy and multicore myopathy with accumulation of intermediate filaments'. Together they form a unique fingerprint.

Cite this