Sarcoglycanopathies are autosomal recessive limb-girdle dystrophies caused by a deficit of one of the four proteins (α, β, γ, δ SG) that constitute the sarcoglycan complex. Cardiac impairment (dilatative cardiomyopathy) has been reported in sporadic cases. In our study we have considered seven patients previously diagnosed as sarcoglycanopathies and we focused our attention on cardiac aspects. In four patients we found a polymorphic cardiac involvement (see text for details). Cardiac impairment in sarcoglycanopathies seems more common and polymorphic than previously reported independently by the primary deficit.
|Translated title of the contribution||Cardiomyopathy in sarcoglycanopathies: Polymorphic clinical aspects|
|Number of pages||8|
|Journal||SAGGI - Neuropsicologia Infantile Psicopedagogia Riabilitazione|
|Publication status||Published - 1998|
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health