ARRESTO CARDIOPLEGICO O ARRESTO ISCHEMICO? IMPIEGO DELLA SOLUZIONE DI BRETSCHNEIDER IN CARDIOCHIRURGIA

Translated title of the contribution: Cardioplegia versus ischemic arrest. The Bretschneider solution in cardiac surgery

L. Menicanti, M. Villani, G. Locatelli

Research output: Contribution to journalArticle

Abstract

The authors compare the degree of myocardial damage caused by an aortic cross clamping 'protected' by the coronary infusion of the Bretschneider solution as cardioplegic agent with that caused by a conventional aortic cross clamping (short and with mild body hypothermia around 32°C). As myocardial damage indexes two parameters, one biochemical and the other morphologic have been studied. In the biochemical study the concentration of several enzymes (CPK, LDH, GOT, GPT, HBDH, Aldolasi), in the coronary sinus blood, has been measured. The morphologic study consisted in electron microscope observation of the right auricolar myocardium before and after the aortic cross clamping. Both studies have been carried out in two groups of patients, the first with and the second without Bretschneider, total number being 32 cases. Biochemical data have been statistically analyzed by a computer to verify their reliability. It was found that both the enzymatic concentration and the cytologic alterations were significantly lower in the cardioplegic group of patients. The authors recommend a wider use of Bretschneider solution as cardioplegic agent in cardiac surgery.

Original languageItalian
Pages (from-to)565-578
Number of pages14
JournalActa Anaesthesiologica Italica
Volume29
Issue number4
Publication statusPublished - 1978

Fingerprint

Induced Heart Arrest
Constriction
Thoracic Surgery
Coronary Sinus
Hypothermia
Myocardium
Observation
Electrons
Enzymes
Bretschneider cardioplegic solution

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

Cite this

ARRESTO CARDIOPLEGICO O ARRESTO ISCHEMICO? IMPIEGO DELLA SOLUZIONE DI BRETSCHNEIDER IN CARDIOCHIRURGIA. / Menicanti, L.; Villani, M.; Locatelli, G.

In: Acta Anaesthesiologica Italica, Vol. 29, No. 4, 1978, p. 565-578.

Research output: Contribution to journalArticle

@article{e756606165a1435d9b5acd5e2902950c,
title = "ARRESTO CARDIOPLEGICO O ARRESTO ISCHEMICO? IMPIEGO DELLA SOLUZIONE DI BRETSCHNEIDER IN CARDIOCHIRURGIA",
abstract = "The authors compare the degree of myocardial damage caused by an aortic cross clamping 'protected' by the coronary infusion of the Bretschneider solution as cardioplegic agent with that caused by a conventional aortic cross clamping (short and with mild body hypothermia around 32°C). As myocardial damage indexes two parameters, one biochemical and the other morphologic have been studied. In the biochemical study the concentration of several enzymes (CPK, LDH, GOT, GPT, HBDH, Aldolasi), in the coronary sinus blood, has been measured. The morphologic study consisted in electron microscope observation of the right auricolar myocardium before and after the aortic cross clamping. Both studies have been carried out in two groups of patients, the first with and the second without Bretschneider, total number being 32 cases. Biochemical data have been statistically analyzed by a computer to verify their reliability. It was found that both the enzymatic concentration and the cytologic alterations were significantly lower in the cardioplegic group of patients. The authors recommend a wider use of Bretschneider solution as cardioplegic agent in cardiac surgery.",
author = "L. Menicanti and M. Villani and G. Locatelli",
year = "1978",
language = "Italian",
volume = "29",
pages = "565--578",
journal = "Acta Anaesthesiologica Italica",
issn = "0374-4965",
publisher = "Edtrice la Garangola",
number = "4",

}

TY - JOUR

T1 - ARRESTO CARDIOPLEGICO O ARRESTO ISCHEMICO? IMPIEGO DELLA SOLUZIONE DI BRETSCHNEIDER IN CARDIOCHIRURGIA

AU - Menicanti, L.

AU - Villani, M.

AU - Locatelli, G.

PY - 1978

Y1 - 1978

N2 - The authors compare the degree of myocardial damage caused by an aortic cross clamping 'protected' by the coronary infusion of the Bretschneider solution as cardioplegic agent with that caused by a conventional aortic cross clamping (short and with mild body hypothermia around 32°C). As myocardial damage indexes two parameters, one biochemical and the other morphologic have been studied. In the biochemical study the concentration of several enzymes (CPK, LDH, GOT, GPT, HBDH, Aldolasi), in the coronary sinus blood, has been measured. The morphologic study consisted in electron microscope observation of the right auricolar myocardium before and after the aortic cross clamping. Both studies have been carried out in two groups of patients, the first with and the second without Bretschneider, total number being 32 cases. Biochemical data have been statistically analyzed by a computer to verify their reliability. It was found that both the enzymatic concentration and the cytologic alterations were significantly lower in the cardioplegic group of patients. The authors recommend a wider use of Bretschneider solution as cardioplegic agent in cardiac surgery.

AB - The authors compare the degree of myocardial damage caused by an aortic cross clamping 'protected' by the coronary infusion of the Bretschneider solution as cardioplegic agent with that caused by a conventional aortic cross clamping (short and with mild body hypothermia around 32°C). As myocardial damage indexes two parameters, one biochemical and the other morphologic have been studied. In the biochemical study the concentration of several enzymes (CPK, LDH, GOT, GPT, HBDH, Aldolasi), in the coronary sinus blood, has been measured. The morphologic study consisted in electron microscope observation of the right auricolar myocardium before and after the aortic cross clamping. Both studies have been carried out in two groups of patients, the first with and the second without Bretschneider, total number being 32 cases. Biochemical data have been statistically analyzed by a computer to verify their reliability. It was found that both the enzymatic concentration and the cytologic alterations were significantly lower in the cardioplegic group of patients. The authors recommend a wider use of Bretschneider solution as cardioplegic agent in cardiac surgery.

UR - http://www.scopus.com/inward/record.url?scp=0018079085&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0018079085&partnerID=8YFLogxK

M3 - Articolo

AN - SCOPUS:0018079085

VL - 29

SP - 565

EP - 578

JO - Acta Anaesthesiologica Italica

JF - Acta Anaesthesiologica Italica

SN - 0374-4965

IS - 4

ER -