Cardiovascular and pulmonary activity of platelet-activating factor (PAF-Acether) and its derivatives

F. Berti, V. Ferri, M. Pallavicini, M. Pretolani, E. Tremoli, E. Valoti, L. Villa

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Stereoselective synthesis and biological properties of PAF-acether, its enantiomer and some analogues of both are reported. The results clearly indicate that the ONIUM SIZE and SHAPE of the various compounds tested are important in determining guinea-pig bronchoconstriction and human platelet aggregation.

Original languageEnglish
Pages (from-to)557-562
Number of pages6
JournalPharmacological Research Communications
Volume18
Issue number6
DOIs
Publication statusPublished - 1986

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Bronchoconstriction
Platelet Activating Factor
Platelet Aggregation
Guinea Pigs
Lung

ASJC Scopus subject areas

  • Pharmacology

Cite this

Cardiovascular and pulmonary activity of platelet-activating factor (PAF-Acether) and its derivatives. / Berti, F.; Ferri, V.; Pallavicini, M.; Pretolani, M.; Tremoli, E.; Valoti, E.; Villa, L.

In: Pharmacological Research Communications, Vol. 18, No. 6, 1986, p. 557-562.

Research output: Contribution to journalArticle

Berti, F. ; Ferri, V. ; Pallavicini, M. ; Pretolani, M. ; Tremoli, E. ; Valoti, E. ; Villa, L. / Cardiovascular and pulmonary activity of platelet-activating factor (PAF-Acether) and its derivatives. In: Pharmacological Research Communications. 1986 ; Vol. 18, No. 6. pp. 557-562.
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