Cardiovascular autonomic control in myotonic dystrophy type 1: A correlative study with clinical and genetic data

Rita Di Leo; Carmelo Rodolico; Cesare De Gregorio; Antonino Recupero; Sebastiano Coglitore; Grazia Annesi; Antonio Toscano; Corrado Messina; Giuseppe Vita

doi:10.1016/j.nmd.2003.11.002

Cardiovascular autonomic control in myotonic dystrophy type 1: A correlative study with clinical and genetic data

Rita Di Leo, Carmelo Rodolico, Cesare De Gregorio, Antonino Recupero, Sebastiano Coglitore, Grazia Annesi, Antonio Toscano, Corrado Messina, Giuseppe Vita

IRCCS Centro Neurolesi "Bonino Pulejo"

Research output: Contribution to journal › Article › peer-review

Abstract

The autonomic nervous system has been evaluated in myotonic dystrophy with contradictory results and its relationship with heart disturbances remains unclear. Twenty-three patients with myotonic dystrophy type 1 were investigated by a battery of six cardiovascular autonomic tests and power spectral analysis of heart rate variability. Although 15 patients (65%) revealed abnormal or borderline results in some tests, only one patient had a definite autonomic damage, as indicated by two or more abnormal tests. As a group, myotonic dystrophy type 1 patients showed a significant reduction of heart rate variability during deep breathing (P

Original language	English
Pages (from-to)	136-141
Number of pages	6
Journal	Neuromuscular Disorders
Volume	14
Issue number	2
DOIs	https://doi.org/10.1016/j.nmd.2003.11.002
Publication status	Published - Feb 2004

Keywords

Autonomic nervous system
Cardiovascular reflex tests
Heart disturbances
Heart rate variability
Myotonic dystrophy type 1
Power spectral analysis

ASJC Scopus subject areas

Clinical Neurology
Pediatrics, Perinatology, and Child Health
Developmental Neuroscience
Neurology

Access to Document

10.1016/j.nmd.2003.11.002

Cite this

Cardiovascular autonomic control in myotonic dystrophy type 1 : A correlative study with clinical and genetic data. / Di Leo, Rita; Rodolico, Carmelo; De Gregorio, Cesare; Recupero, Antonino; Coglitore, Sebastiano; Annesi, Grazia; Toscano, Antonio; Messina, Corrado; Vita, Giuseppe.

In: Neuromuscular Disorders, Vol. 14, No. 2, 02.2004, p. 136-141.

Research output: Contribution to journal › Article › peer-review

@article{1de67c630b8a42118d275b9e5e450a5f,

title = "Cardiovascular autonomic control in myotonic dystrophy type 1: A correlative study with clinical and genetic data",

abstract = "The autonomic nervous system has been evaluated in myotonic dystrophy with contradictory results and its relationship with heart disturbances remains unclear. Twenty-three patients with myotonic dystrophy type 1 were investigated by a battery of six cardiovascular autonomic tests and power spectral analysis of heart rate variability. Although 15 patients (65%) revealed abnormal or borderline results in some tests, only one patient had a definite autonomic damage, as indicated by two or more abnormal tests. As a group, myotonic dystrophy type 1 patients showed a significant reduction of heart rate variability during deep breathing (P",

keywords = "Autonomic nervous system, Cardiovascular reflex tests, Heart disturbances, Heart rate variability, Myotonic dystrophy type 1, Power spectral analysis",

author = "{Di Leo}, Rita and Carmelo Rodolico and {De Gregorio}, Cesare and Antonino Recupero and Sebastiano Coglitore and Grazia Annesi and Antonio Toscano and Corrado Messina and Giuseppe Vita",

year = "2004",

month = feb,

doi = "10.1016/j.nmd.2003.11.002",

language = "English",

volume = "14",

pages = "136--141",

journal = "Neuromuscular Disorders",

issn = "0960-8966",

publisher = "Elsevier Ltd",

number = "2",

}

TY - JOUR

T1 - Cardiovascular autonomic control in myotonic dystrophy type 1

T2 - A correlative study with clinical and genetic data

AU - Di Leo, Rita

AU - Rodolico, Carmelo

AU - De Gregorio, Cesare

AU - Recupero, Antonino

AU - Coglitore, Sebastiano

AU - Annesi, Grazia

AU - Toscano, Antonio

AU - Messina, Corrado

AU - Vita, Giuseppe

PY - 2004/2

Y1 - 2004/2

N2 - The autonomic nervous system has been evaluated in myotonic dystrophy with contradictory results and its relationship with heart disturbances remains unclear. Twenty-three patients with myotonic dystrophy type 1 were investigated by a battery of six cardiovascular autonomic tests and power spectral analysis of heart rate variability. Although 15 patients (65%) revealed abnormal or borderline results in some tests, only one patient had a definite autonomic damage, as indicated by two or more abnormal tests. As a group, myotonic dystrophy type 1 patients showed a significant reduction of heart rate variability during deep breathing (P

AB - The autonomic nervous system has been evaluated in myotonic dystrophy with contradictory results and its relationship with heart disturbances remains unclear. Twenty-three patients with myotonic dystrophy type 1 were investigated by a battery of six cardiovascular autonomic tests and power spectral analysis of heart rate variability. Although 15 patients (65%) revealed abnormal or borderline results in some tests, only one patient had a definite autonomic damage, as indicated by two or more abnormal tests. As a group, myotonic dystrophy type 1 patients showed a significant reduction of heart rate variability during deep breathing (P

KW - Autonomic nervous system

KW - Cardiovascular reflex tests

KW - Heart disturbances

KW - Heart rate variability

KW - Myotonic dystrophy type 1

KW - Power spectral analysis

UR - http://www.scopus.com/inward/record.url?scp=0347090625&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0347090625&partnerID=8YFLogxK

U2 - 10.1016/j.nmd.2003.11.002

DO - 10.1016/j.nmd.2003.11.002

M3 - Article

C2 - 14733960

AN - SCOPUS:0347090625

VL - 14

SP - 136

EP - 141

JO - Neuromuscular Disorders

JF - Neuromuscular Disorders

SN - 0960-8966

IS - 2

ER -

Cardiovascular autonomic control in myotonic dystrophy type 1: A correlative study with clinical and genetic data

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this