Objectives: Even though cancer survival has increased due to both the earlier diagnosis of disease and to the increasingly effective treatments, the side effects of cancer treatments, such as cardiotoxicity, remain clinically important. In fact, the prognosis of cancer patients is worsened by increased cardiovascular mortality and morbidity. This review aims to summarize the main cardiotoxic effects of conventional anticancer therapy, although still widely used and effective, and to verify the most effective treatments and the best preventive strategies. Conclusions: A careful cardiac evaluation before, during and after each chemotherapy treatment is needed to minimize the late cardiotoxic effects of traditional chemotherapy.
- Cancer therapy
- Cardiac prevention
- Heart failure
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
- Radiology Nuclear Medicine and imaging