Cardiovascular effects of acute hyperglycaemia: Pathophysiological underpinnings

Research output: Contribution to journalArticle

Abstract

High admission blood glucose levels after acute myocardial infarction are common and are associated with an increased risk of death in subjects with and without diabetes. In this review, the possible toxic effects of acute hyperglycaemia are discussed as a possible explanation for the worse prognosis in subjects with myocardial infarction and concomitant hyperglycaemia. In particular, evidence supporting the hypothesis that acute hyperglycaemia may favour the appearance of cardiovascular disease through the generation of oxidative stress is presented.

Original languageEnglish
Pages (from-to)260-268
Number of pages9
JournalDiabetes and Vascular Disease Research
Volume5
Issue number4
DOIs
Publication statusPublished - Nov 2008

Keywords

  • Endothelial dysfuntion
  • Oxidative stress
  • Postprandial hyperglycaemia

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Endocrinology, Diabetes and Metabolism
  • Internal Medicine

Fingerprint Dive into the research topics of 'Cardiovascular effects of acute hyperglycaemia: Pathophysiological underpinnings'. Together they form a unique fingerprint.

  • Cite this