Cardiovascular Involvement in Psoriatic Arthritis

F. Atzeni, F. Caso, I. F. Masala, P. Sarzi-Puttini

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Psoriatic arthritis is a chronic inflammatory condition in which unbalanced inflammatory pathways act as key drivers of a wide range of articular and extraarticular manifestations. It is associated with a high prevalence of cardiovascular (CV) disease and risk factors. The precise pathogenetic mechanism of CV involvement has still to be clarified, but certain inflammatory cytokines play a key role in the atherosclerotic process. Studies have shown the potentially beneficial role of disease-modifying antirheumatic drug–induced immunosuppression and also anti–tumor necrosis factor drugs on CV diseases.

Original languageEnglish
Title of host publicationHandbook of Systemic Autoimmune Diseases
PublisherElsevier Ltd
Pages409-426
Number of pages18
Volume14
DOIs
Publication statusPublished - Jan 1 2017

Publication series

NameHandbook of Systemic Autoimmune Diseases
Volume14
ISSN (Print)1571-5078

Keywords

  • Antirheumatic drug
  • Atherosclerosis
  • Cardiovascular involvement
  • Mortality
  • Psoriatic arthritis
  • Tumor necrosis factor

ASJC Scopus subject areas

  • Immunology and Allergy
  • Endocrinology, Diabetes and Metabolism

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