Cardiovascular magnetic resonance in systemic sclerosis

“Pearls and pitfalls”

Sophie I. Mavrogeni, Juerg Schwitter, Luna Gargani, Alessia Pepe, Lorenzo Monti, Yannick Allanore, Marco Matucci-Cerinic

Research output: Contribution to journalReview article

13 Citations (Scopus)

Abstract

Systemic sclerosis (SSc) is an autoimmune disease characterized by vascular dysfunction and excessive fibrosis, involving internal organs including the heart. The estimated prevalence of cardiac involvement in SSc is high and remains subclinical until the late stages. It is either primary, related to myocardial inflammation and fibrosis, or secondary, due to pulmonary arterial hypertension (SSc-PAH) or systemic hypertension, in those patients with renal involvement. Cardiovascular magnetic resonance (CMR) is a useful tool for the early assessment of cardiac involvement in SSc. It is the gold standard technique to assess ventricular volumes,ejection fraction, and in particular is very useful to reliably and non-invasively detect myocardial inflammation, early perfusion defects, and myocardial fibrosis. However, the CMR evaluation in SSc may be problematic, because of cardiac and respiratory artefacts, commonly found in these patients. Therefore, a high level of expertise is necessary for both acquisition and interpretation of CMR images in SSc.

Original languageEnglish
Pages (from-to)79-85
Number of pages7
JournalSeminars in Arthritis and Rheumatism
Volume47
Issue number1
DOIs
Publication statusPublished - Aug 1 2017

Fingerprint

Systemic Scleroderma
Magnetic Resonance Spectroscopy
Fibrosis
Inflammation
Pulmonary Hypertension
Stroke Volume
Artifacts
Autoimmune Diseases
Blood Vessels
Perfusion
Hypertension
Kidney

Keywords

  • Cardiac catheterization
  • Cardiovascular magnetic resonance imaging
  • ECG
  • Echocardiography
  • Systemic sclerosis

ASJC Scopus subject areas

  • Rheumatology
  • Anesthesiology and Pain Medicine

Cite this

Mavrogeni, S. I., Schwitter, J., Gargani, L., Pepe, A., Monti, L., Allanore, Y., & Matucci-Cerinic, M. (2017). Cardiovascular magnetic resonance in systemic sclerosis: “Pearls and pitfalls”. Seminars in Arthritis and Rheumatism, 47(1), 79-85. https://doi.org/10.1016/j.semarthrit.2017.03.020

Cardiovascular magnetic resonance in systemic sclerosis : “Pearls and pitfalls”. / Mavrogeni, Sophie I.; Schwitter, Juerg; Gargani, Luna; Pepe, Alessia; Monti, Lorenzo; Allanore, Yannick; Matucci-Cerinic, Marco.

In: Seminars in Arthritis and Rheumatism, Vol. 47, No. 1, 01.08.2017, p. 79-85.

Research output: Contribution to journalReview article

Mavrogeni, SI, Schwitter, J, Gargani, L, Pepe, A, Monti, L, Allanore, Y & Matucci-Cerinic, M 2017, 'Cardiovascular magnetic resonance in systemic sclerosis: “Pearls and pitfalls”', Seminars in Arthritis and Rheumatism, vol. 47, no. 1, pp. 79-85. https://doi.org/10.1016/j.semarthrit.2017.03.020
Mavrogeni, Sophie I. ; Schwitter, Juerg ; Gargani, Luna ; Pepe, Alessia ; Monti, Lorenzo ; Allanore, Yannick ; Matucci-Cerinic, Marco. / Cardiovascular magnetic resonance in systemic sclerosis : “Pearls and pitfalls”. In: Seminars in Arthritis and Rheumatism. 2017 ; Vol. 47, No. 1. pp. 79-85.
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