Caribbean parkinsonism and other atypical Parkinsonian disorders

Eduardo Tolosa, Daniela Calandrella, Marisol Gallardo

Research output: Contribution to journalArticlepeer-review


Atypical parkinsonism (AP) is a term applied to disorders characterized by parkinsonism that evolves rapidly, with poor or transient response to levodopa, or has other associated features such as early falls and postural instability, early autonomic failure, supranuclear gaze palsy, pyramidal or cerebellar signs, alien hand syndrome or severe ideomotor apraxia. The most common AP are multiple system atrophy, progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD). Other APs include Caribbean parkinsonism (CP) and parkinsonism-dementia complex of Guam (PDC). In this review we provide an update in etiology, neuropathology, diagnosis and treatment of atypical parkinsonian disorders associated with protein tau deposit, also known as tauopathies.

Original languageEnglish
JournalParkinsonism and Related Disorders
Issue numberSUPPL. 1
Publication statusPublished - May 2004


  • Atypical parkinsonism
  • Caribbean parkinsonism
  • Corticobasal degeneration
  • Parkinsonism-dementia Guam complex
  • Progressive supranuclear palsy

ASJC Scopus subject areas

  • Ageing
  • Clinical Neurology
  • Neurology


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