Carotid Artery Intima-media Thickness in Nonalcoholic Fatty Liver Disease

Anna Ludovica Fracanzani, Larry Burdick, Sara Raselli, Paola Pedotti, Liliana Grigore, Gennaro Santorelli, Luca Valenti, Alessandra Maraschi, Alberico Catapano, Silvia Fargion

Research output: Contribution to journalArticle

Abstract

Purpose: To evaluate, in patients with nonalcoholic fatty liver disease with no or mild alterations of liver function tests, carotid artery intima-media thickness and the presence of plaques and to define determinants of vascular damage. Methods: A paired-sample case-control study: 125 patients with nonalcoholic fatty liver disease and 250 controls, without a prior diagnosis of diabetes, hypertension, and cardiovascular disease, matched for sex, age, and body mass index. B-mode ultrasound was used for evaluation of carotid intima-media thickness and presence of small plaques. Results: A significant difference in mean values of intima-media thickness (0.89 ± 0.26 and 0.64 ± 0.14 mm, P = .0001) and prevalence of plaques (26 [21%] and 15 [6%], P

Original languageEnglish
Pages (from-to)72-78
Number of pages7
JournalAmerican Journal of Medicine
Volume121
Issue number1
DOIs
Publication statusPublished - Jan 2008

Keywords

  • IMT
  • metabolic syndrome
  • NAFLD

ASJC Scopus subject areas

  • Nursing(all)

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