Carotid artery stenting in patients with acute coronary syndrome: A possible primary therapy for symptomatic carotid stenosis

Renato Casana, Alison Halliday, Paolo Bianchi, Emanuele Fresa, Vincenzo Silani, Gianfranco Parati, Simonetta Blengino, Lea Cireni, Laura Adobbati, Laura Calvillo, Valerio S. Tolva

Research output: Contribution to journalArticle

Abstract

Purpose: To report the results of carotid artery stenting (CAS) in symptomatic patients (stroke/transient ischemic attack) after recent percutaneous transluminal coronary angioplasty (PTCA) for acute coronary syndrome (ACS). Methods: Between January 2009 and July 2011, 28 consecutive patients (18 women; mean age 66 years, range 42-82) underwent protected CAS for symptomatic carotid stenosis following recent PTCA that included bare or drug-eluting stents requiring uninterrupted dual antiplatelet therapy. Primary technical success, neurological complications, major adverse cardiovascular events, and death were evaluated at 30 days and over midterm follow-up. Results: Technical success was 96%; 1 patient suffered a nonfatal major stroke (3.5% 30-day stroke rate) during the procedure. During a median 21.6-month follow-up, 4 (14%) patients died of myocardial infarction (all diabetic smokers with ejection fractions 34 kg/m2. Conclusion: This preliminary experience demonstrated that CAS is a reasonable, safe, and effective treatment for patients with symptomatic carotid artery stenosis who were recently treated with coronary stents requiring uninterrupted dual antiplatelet therapy.

Original languageEnglish
Pages (from-to)546-551
Number of pages6
JournalJournal of Endovascular Therapy
Volume20
Issue number4
DOIs
Publication statusPublished - Aug 2013

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Keywords

  • Carotid artery stenting
  • Carotid stenosis
  • Cerebral protection
  • Coronary angioplasty
  • Coronary artery disease
  • Myocardial infarction
  • Percutaneous coronary intervention
  • Stroke

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Radiology Nuclear Medicine and imaging

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