Carotid intima-media thickness is not associated with vitamin D and PTH levels in patients admitted to an Internal Medicine Department

Vincenzo Carnevale, Rita Minonne, Angela De Matthaeis, Maria Antonietta Annese, Patrizia Tabacco, Palmina D’Arcangelo, Graziella D’Amico, Alfredo Scillitani

Research output: Contribution to journalArticle

Abstract

Vitamin D (25OHD) and/or parathyroid hormone (PTH) levels have been associated with common carotid intima-media thickness (IMT). We investigated such associations in inpatients consecutively admitted to an Internal Medicine Department. In 168 consecutive patients admitted to our department, 25 hydroxyvitamin D (25OHD) was measured by means of RIA and PTH by means of ICMA, whereas IMT by means of ultrasonography. The main cardiovascular risk factors were also explored. In patients with either diabetes, or hypertension, or both, 25OHD values were not significantly lower than in other patients. No difference was found among the IMT values across tertiles of 25OHD level, as like as in the 25OHD, PTH, PTH/25OHD ratio values of patients either grouped by tertiles of IMT, or categorized according to IMT of 1.5 mm. IMT did not significantly associate with 25OHD, PTH, and PTH/25OHD ratio, whereas it positively associated with age (r = 0.281; p 

Original languageEnglish
Pages (from-to)833-838
Number of pages6
JournalEndocrine
Volume47
Issue number3
DOIs
Publication statusPublished - Nov 21 2014

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Keywords

  • Inpatients
  • Intima-media thickness
  • PTH
  • PTH/vitamin D ratio
  • Vitamin D

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism
  • Medicine(all)

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