Carotid protection devices: Rationale and clinical results

Goran Stankovic, D. Orlic, A. Colombo

Research output: Contribution to journalArticlepeer-review

Abstract

During the last decade interventional revascularisation procedures of vessels supplying the brain have been developed as an alternative to medical and surgical treatment. However, there has been concern regarding their safety because of the risk of cerebral embolisation during the procedure. In the Carotid And Vertebral Artery Transluminal Angioplasty Study (CAVATAS), 504 patients with symptomatic carotid stenosis were randomised to either balloon angioplasty (bail-out stenting was performed in 26%) or carotid endarterectomy (CEA). CAVATAS demonstrated equal benefit for prevention of stroke and death in both groups at 30 days (incidence of any stroke lasting more than 7 days or death was 10%), which was sustained for three years. The pioneering work of Yadav on 107 high-risk patients (45% were referred by surgeons) treated with elective carotid artery stenting (CAS) was published in 1997. The procedure was successful in all patients and the incidence of the combined endpoint of all strokes and death was 7.9%.

Original languageEnglish
Pages (from-to)47-54
Number of pages8
JournalCardiology International
Volume6
Issue number2
Publication statusPublished - Jun 2005

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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