Carriage of methicillin-resistant Staphylococcus aureus on admission to European rehabilitation centres-a prospective study

E. Bilavsky, Y. Lerman, A. Rabinovich, J. Salomon, C. Lawrence, A. Rossini, A. Salvia, J. V. Samso, J. Fierro, M. Hochman, M. Kazma, A. Klein, M. J. Schwaber, Y. Carmeli, B. Efraim, Christian Brun-Buisson, Susana Camps, Rita Formisano, Maria Pia, Balice Emilio GuaglianoneJennifer Lasley, Inga Bertucci, Marie Laure Delaby, Cecile Colmant, Catherne Sacleux, Herman Goossens, Surbhi Malhotra Kumar, Christine Lammens, Michal Paul, Jacov Hart, Eli Isakov, Alexander Friedman, Aliza Rachman, Gita Franco, Ilanaor Loewenstein, Shiri Navon-Venezia, Maya Shklyar, Lilach Keren, Rivka Glick, Shiri Klarfeld-Lidji, Eti Mordechai, Shimrit Cohen, Ruth Fachima, Yelena Zdonevsky

Research output: Contribution to journalArticlepeer-review

Abstract

This study aimed to determine the prevalence of and risk factors for methicillin-resistant Staphylococcus aureus (MRSA) carriage among patients newly admitted to rehabilitation centres. It is a prospective study examining MRSA carriage on admission to seven rehabilitation wards in four countries. Risk factors for MRSA carriage were analysed using univariate and multivariate analyses. A total of 1204 patients were studied. Among them, 105 (8.7%) had a positive admission MRSA screening result. The MRSA carriers were more likely to be male, to have had a recent stay in another long-term-care facility or >2weeks acute-care hospital stay, history of colonization with MRSA, reduced level of consciousness, peripheral vascular disease and pressure sores. In multivariable logistic regression male gender (odds ratio (OR) 2.2, 95% confidence interval (CI) 1.4-3.6, p0.001), history of MRSA positivity (OR 6.8, 95% CI 3.8-12.3, p2weeks) acute-care hospital stay (OR 1.9, 95% CI 1.2-3, p0.004), remained significant risk factors for MRSA carriage. MRSA carriage is common on admission to rehabilitation centres but less so, than previously described in long-term-care facilities. Male gender, history of MRSA positivity, previous hospitalization and peripheral vascular disease may predict MRSA carriage, and may serve as indicators for using pre-emptive infection control measures.

Original languageEnglish
JournalClinical Microbiology and Infection
Volume18
Issue number6
DOIs
Publication statusPublished - Jun 2012

Keywords

  • Long-term-care
  • Methicillin-resistant staphylococcus aureus
  • Rehabilitation

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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