Case-control registry of excimer laser coronary angioplasty versus distal protection devices in patients with acute coronary syndromes due to saphenous vein graft disease

Giampaolo Niccoli, Flavia Belloni, Nicola Cosentino, Francesco Fracassi, Elena Falcioni, Marco Roberto, Roberta Antonazzo Panico, Rocco Mongiardo, Italo Porto, Antonio Maria Leone, Francesco Burzotta, Carlo Trani, Filippo Crea

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Abstract

Laser atherectomy might decrease procedural complications during percutaneous coronary intervention (PCI) of degenerated saphenous vein grafts (SVGs) in case of unstable or thrombotic lesions because of its ability to debulk and vaporize thrombus. We aimed at prospectively evaluating the safety and efficacy of excimer laser coronary angioplasty (ELCA) as a primary treatment strategy in consecutively unstable patients undergoing PCI of degenerated SVG lesions. Seventy-one consecutive patients with non-ST elevation acute coronary syndrome (mean age 69 ± 10 years, 66 men [89%]) undergoing PCI of degenerated SVG were enrolled in a prospective case-control registry, using 2 different distal protection devices (DPDs; FilterWire EZ [Boston Scientific, Natick, Massachusetts; n = 24] and SpiderRX [Ev3, Plymouth, Minnesota; n = 23]) or ELCA (n = 24). Primary end points of the study were incidence of angiographic microvascular obstruction (Thrombolysis In Myocardial Infarction flow grade of

Original languageEnglish
Pages (from-to)1586-1591
Number of pages6
JournalThe American Journal of Cardiology
Volume112
Issue number10
DOIs
Publication statusPublished - Nov 15 2013

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ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Niccoli, G., Belloni, F., Cosentino, N., Fracassi, F., Falcioni, E., Roberto, M., Panico, R. A., Mongiardo, R., Porto, I., Leone, A. M., Burzotta, F., Trani, C., & Crea, F. (2013). Case-control registry of excimer laser coronary angioplasty versus distal protection devices in patients with acute coronary syndromes due to saphenous vein graft disease. The American Journal of Cardiology, 112(10), 1586-1591. https://doi.org/10.1016/j.amjcard.2013.07.015