Case of melorheostosis associated with ipsilateral verrucous epidermal nevus, linear connective tissue nevus, diffuse hyperpigmentation and hypertrichosis: A fortuitous coincidence?

Ambra Di Altobrando, Iria Neri, Carlotta Gurioli, Cosimo Misciali, Carlotta Baraldi, Elena Pedrini, Maria Gnoli, Morena Tremosini, Luca Sangiorgi, Annalisa Patrizi

Research output: Contribution to journalArticlepeer-review

Abstract

Melorheostosis (MEL) is a rare benign bone disorder that can be associated with several anomalies, including vascular abnormalities, nevus sebaceus, unilateral nevoid telangiectasia, linear scleroderma and hypertrichosis. We report the case of a 6-year-old patient who showed an unusual co-occurrence of bone hyperostosis and different skin lesions affecting the same side of the body: MEL, verrucous epidermal nevus, connective tissue nevus, linear scleroderma-like disorder, hyperpigmentation and hypertrichosis. The spatial co-occurrence of these conditions made us speculate as to whether they originated from a common genetic mechanism or if their co-occurrence was completely accidental.

Original languageEnglish
Pages (from-to)1063-1066
Number of pages4
JournalJournal of Dermatology
Volume47
Issue number9
Early online dateJul 12 2020
DOIs
Publication statusPublished - Sep 2020

Keywords

  • connective tissue nevus
  • hyperpigmentation
  • hypertrichosis
  • melorheostosis
  • verrucous epidermal nevus

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