Case Report: All That Glisters Is Not* Cancer

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Properly performed staging in non-small-cell lung cancer (NSCLC) is necessary to avoid wrong therapeutic decisions. Here we present a case which manifested as advanced NSCLC but ultimately was composed of two different and rare pathologies. The first is a TTF-1 positive axillary lymph node that could be defined either as an unusual isolated differentiated cancer of unknown primary or as an even rarer case of ectopic lung epithelium which underwent malignant transformation. The second is sarcoidosis, a sarcoid-like alteration, in remission after oral steroids. The main implication of a correct diagnosis regards patient outcome and the avoidance of toxic inappropriate systemic chemotherapy.

Original languageEnglish
Article number541629
JournalFrontiers in Medicine
Publication statusPublished - Nov 30 2020


  • lung cancer
  • metastases
  • origin
  • sarcoidosis
  • staging

ASJC Scopus subject areas

  • Medicine(all)


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