Case Report: Successful Treatment with Cimetidine and Zinc Sulphate in Chronic Mucocutaneous Candidiasis

Biancamaria Polizzi, Laura Origgi, Giovanni Zuccaro, Paola Matti, Raffaella Scorza

Research output: Contribution to journalArticlepeer-review

Abstract

The authors evaluated the clinical efficacy of a treatment with cimetidine and zinc sulphate in a patient with chronic mucocutaneous candidiasis. Cimetidine was given at a dose of 400 mg three times daily; zinc sulphate at a dose of 200 mg daily, then adjusted to maintain blood zinc levels at the upper normal range. This treatment lasted 16 months. An impressive and significant reduction of the infectious events and an increased CD4 (helper/inducer) cell counts were observed. The authors conclude that this combined immunopotentiating treatment is safe and inexpensive to treat immunodeficiency disorders.

Original languageEnglish
Pages (from-to)189-190
Number of pages2
JournalAmerican Journal of the Medical Sciences
Volume311
Issue number4
Publication statusPublished - Apr 1996

Keywords

  • Candidiasis
  • Cimetidine
  • Zinc

ASJC Scopus subject areas

  • Medicine(all)

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