Caspofungin associated with liposomal amphotericin B or voriconazole for treatment of refractory fungal pneumonia in children with acute leukamia or undergoing allogeneic bone narrow transplant

Elio Castagnola, M. Machetti, B. Cappelli, A. C. Molinari, G. Morreale, P. Dodero, P. Tomà, M. Faraci

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Caspofungin, in association with other antifungal drugs, was administered as rescue therapy in two cases of documented and one case of possible invasive fungal infection in children with acute leukaemia or undergoing allogeneic bone marrow transplant. The combined therapy was well-tolerated and seemed to be effective in all three patients. A combination antifungal therapy including caspofungin could represent an effective therapy for children with invasive mycoses refractory to single-agent antifungal therapy.

Original languageEnglish
Pages (from-to)255-257
Number of pages3
JournalClinical Microbiology and Infection
Volume10
Issue number3
DOIs
Publication statusPublished - Mar 2004

Fingerprint

caspofungin
Pneumonia
Transplants
Bone and Bones
Therapeutics
Antifungal Agents
Leukemia
Bone Marrow
liposomal amphotericin B
Voriconazole

Keywords

  • Amphotericin B
  • Bone marrow transplant
  • Caspofungin
  • Fungal pneumonia
  • Leukaemia
  • Voriconazole

ASJC Scopus subject areas

  • Microbiology (medical)
  • Microbiology
  • Infectious Diseases

Cite this

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abstract = "Caspofungin, in association with other antifungal drugs, was administered as rescue therapy in two cases of documented and one case of possible invasive fungal infection in children with acute leukaemia or undergoing allogeneic bone marrow transplant. The combined therapy was well-tolerated and seemed to be effective in all three patients. A combination antifungal therapy including caspofungin could represent an effective therapy for children with invasive mycoses refractory to single-agent antifungal therapy.",
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T1 - Caspofungin associated with liposomal amphotericin B or voriconazole for treatment of refractory fungal pneumonia in children with acute leukamia or undergoing allogeneic bone narrow transplant

AU - Castagnola, Elio

AU - Machetti, M.

AU - Cappelli, B.

AU - Molinari, A. C.

AU - Morreale, G.

AU - Dodero, P.

AU - Tomà, P.

AU - Faraci, M.

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AB - Caspofungin, in association with other antifungal drugs, was administered as rescue therapy in two cases of documented and one case of possible invasive fungal infection in children with acute leukaemia or undergoing allogeneic bone marrow transplant. The combined therapy was well-tolerated and seemed to be effective in all three patients. A combination antifungal therapy including caspofungin could represent an effective therapy for children with invasive mycoses refractory to single-agent antifungal therapy.

KW - Amphotericin B

KW - Bone marrow transplant

KW - Caspofungin

KW - Fungal pneumonia

KW - Leukaemia

KW - Voriconazole

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