Catch-up growth in body mass index is associated neither with reduced insulin sensitivity nor with altered lipid profile in children born small for gestational age

P. Torre, C. Ladaki, G. Scirè, G. L. Spadoni, Stefano Cianfarani

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Objective: Low birth weight is a risk factor for coronary heart disease. Persons who have coronary events as adults tend to have been small at birth and thin at 2 yr of age, after which they tended to increase their body mass index (BMI). Our aim was to determine whether BMI gain is associated to alterations in insulin sensitivity and/or lipid profile in children born small for gestational age (SGA). Design: Retrospective case-control study. Methods: We studied 78 children (mean age 7.8±2.5 yr): 26 SGA children with catch-up growth in BMI (CGB-SGA) (BMI= 10th to 75th centile), 26 SGA without catch-up growth (NCGB-SGA) (BMI

Original languageEnglish
Pages (from-to)760-764
Number of pages5
JournalJournal of Endocrinological Investigation
Volume31
Issue number9
Publication statusPublished - Sep 2008

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Gestational Age
Insulin Resistance
Body Mass Index
Lipids
Growth
Low Birth Weight Infant
Coronary Disease
Case-Control Studies
Parturition

Keywords

  • BMI
  • Insulin sensitivity
  • Lipid
  • SGA (small for gestational age)

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

Cite this

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title = "Catch-up growth in body mass index is associated neither with reduced insulin sensitivity nor with altered lipid profile in children born small for gestational age",
abstract = "Objective: Low birth weight is a risk factor for coronary heart disease. Persons who have coronary events as adults tend to have been small at birth and thin at 2 yr of age, after which they tended to increase their body mass index (BMI). Our aim was to determine whether BMI gain is associated to alterations in insulin sensitivity and/or lipid profile in children born small for gestational age (SGA). Design: Retrospective case-control study. Methods: We studied 78 children (mean age 7.8±2.5 yr): 26 SGA children with catch-up growth in BMI (CGB-SGA) (BMI= 10th to 75th centile), 26 SGA without catch-up growth (NCGB-SGA) (BMI",
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T1 - Catch-up growth in body mass index is associated neither with reduced insulin sensitivity nor with altered lipid profile in children born small for gestational age

AU - Torre, P.

AU - Ladaki, C.

AU - Scirè, G.

AU - Spadoni, G. L.

AU - Cianfarani, Stefano

PY - 2008/9

Y1 - 2008/9

N2 - Objective: Low birth weight is a risk factor for coronary heart disease. Persons who have coronary events as adults tend to have been small at birth and thin at 2 yr of age, after which they tended to increase their body mass index (BMI). Our aim was to determine whether BMI gain is associated to alterations in insulin sensitivity and/or lipid profile in children born small for gestational age (SGA). Design: Retrospective case-control study. Methods: We studied 78 children (mean age 7.8±2.5 yr): 26 SGA children with catch-up growth in BMI (CGB-SGA) (BMI= 10th to 75th centile), 26 SGA without catch-up growth (NCGB-SGA) (BMI

AB - Objective: Low birth weight is a risk factor for coronary heart disease. Persons who have coronary events as adults tend to have been small at birth and thin at 2 yr of age, after which they tended to increase their body mass index (BMI). Our aim was to determine whether BMI gain is associated to alterations in insulin sensitivity and/or lipid profile in children born small for gestational age (SGA). Design: Retrospective case-control study. Methods: We studied 78 children (mean age 7.8±2.5 yr): 26 SGA children with catch-up growth in BMI (CGB-SGA) (BMI= 10th to 75th centile), 26 SGA without catch-up growth (NCGB-SGA) (BMI

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KW - Insulin sensitivity

KW - Lipid

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