Catheter-related thrombosis in hematologic patients

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

For many years central venous catheters (CVC) have been utilized to monitor hemodynamics and to deliver parenteral nutrition, blood products, pharmacological therapies or infusion fluids. Recently, CVC use has greatly increased with significant impact on the administration of chemotherapy, stem cell transplantation and other treatments to cancer patients. However, CVC use may be accompanied by a variety of side-effects, which increase with the duration of implantation. The most common catheter-related complications are thrombotic events and blood-stream infections. The true incidence of these complications is still uncertain and has changed over time due to CVC device improvement. More data are available in solid tumor than in oncohematologic patients. Recently, much attention has been paid to the issues of prevention and treatment of these complications. Some strategies have been proposed: fixed dose warfarin or low molecular weight heparins have been evaluated in some clinical trials of thromboprophylaxis in this condition. However, more studies are still needed to address this issue. This review will focus on CVC use and complications in oncohematologic patients.

Original languageEnglish
JournalReviews in Clinical and Experimental Hematology
Volume8
Issue number1
Publication statusPublished - Jun 2004

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Central Venous Catheters
Thrombosis
Catheters
Low Molecular Weight Heparin
Parenteral Nutrition
Stem Cell Transplantation
Warfarin
Neoplasms
Therapeutics
Hemodynamics
Clinical Trials
Pharmacology
Drug Therapy
Equipment and Supplies
Incidence
Infection

ASJC Scopus subject areas

  • Hematology

Cite this

Catheter-related thrombosis in hematologic patients. / Moia, Marco; Cortelezzi, Agostino; Falanga, Anna.

In: Reviews in Clinical and Experimental Hematology, Vol. 8, No. 1, 06.2004.

Research output: Contribution to journalArticle

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