Caudate nucleus abnormalities in obsessive-compulsivedisorder: Measurements of MRI signal intensity

Giovanna Calabrese; Cristina Colombo; Anna Bonfanti; Giuseppe Scotti; Silvio Scarone

Caudate nucleus abnormalities in obsessive-compulsivedisorder: Measurements of MRI signal intensity

Giovanna Calabrese, Cristina Colombo, Anna Bonfanti, Giuseppe Scotti, Silvio Scarone

IRCCS Ospedale San Raffaele

Research output: Contribution to journal › Article › peer-review

Abstract

A previous magnetic resonance imaging (MRI) study from our groupreported increased size of the right caudate nucleus in obsessive-compulsive patients compared with control subjects. To test the hypothesis of a structural abnormality underlying such volume alteration, MRI signal intensity (SI), as an index of T₁ relaxation values, was measured in the caudate nucleus of the same sampling data. Results showed higher SI values in the left caudate nucleus compared with the right in the patient group, whereas no asymmetry was found in the control group.

Original language	English
Pages (from-to)	89-92
Number of pages	4
Journal	Psychiatry Research
Volume	50
Issue number	2
Publication status	Published - Jun 1993

Keywords

basalganglia
laterality
Magnetic resonance imaging
striatum
T relaxation time

ASJC Scopus subject areas

Psychology(all)
Biological Psychiatry
Psychiatry and Mental health
Radiology Nuclear Medicine and imaging

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abstract = "A previous magnetic resonance imaging (MRI) study from our groupreported increased size of the right caudate nucleus in obsessive-compulsive patients compared with control subjects. To test the hypothesis of a structural abnormality underlying such volume alteration, MRI signal intensity (SI), as an index of T1 relaxation values, was measured in the caudate nucleus of the same sampling data. Results showed higher SI values in the left caudate nucleus compared with the right in the patient group, whereas no asymmetry was found in the control group.",

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AU - Scotti, Giuseppe

AU - Scarone, Silvio

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AB - A previous magnetic resonance imaging (MRI) study from our groupreported increased size of the right caudate nucleus in obsessive-compulsive patients compared with control subjects. To test the hypothesis of a structural abnormality underlying such volume alteration, MRI signal intensity (SI), as an index of T1 relaxation values, was measured in the caudate nucleus of the same sampling data. Results showed higher SI values in the left caudate nucleus compared with the right in the patient group, whereas no asymmetry was found in the control group.

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KW - laterality

KW - Magnetic resonance imaging

KW - striatum

KW - T relaxation time

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