Abstract
Successful motor interactions require agents to anticipate what a partner is doing in order to predictively adjust their own movements. Although the neural underpinnings of the ability to predict others € action goals have been well explored during passive action observation, no study has yet clarified any critical neural substrate supporting interpersonal coordination during active, non-imitative (complementary) interactions. Here, we combine non-invasive inhibitory brain stimulation (continuous Theta Burst Stimulation) with a novel human-Avatar interaction task to investigate a causal role for higher-order motor cortical regions in supporting the ability to predict and adapt to others € actions. We demonstrate that inhibition of left anterior intraparietal sulcus (aIPS), but not ventral premotor cortex, selectively impaired individuals € performance during complementary interactions. Thus, in addition to coding observed and executed action goals, aIPS is crucial in coding € shared goals €, that is, integrating predictions about one € s and others € complementary actions.
| Original language | English |
|---|---|
| Article number | 7544 |
| Journal | Nature Communications |
| Volume | 6 |
| DOIs | |
| Publication status | Published - Jul 8 2015 |
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ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Chemistry(all)
- Physics and Astronomy(all)
Cite this
Causative role of left aIPS in coding shared goals during human-Avatar complementary joint actions. / Sacheli, Lucia M.; Candidi, Matteo; Era, Vanessa; Aglioti, Salvatore M.
In: Nature Communications, Vol. 6, 7544, 08.07.2015.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Causative role of left aIPS in coding shared goals during human-Avatar complementary joint actions
AU - Sacheli, Lucia M.
AU - Candidi, Matteo
AU - Era, Vanessa
AU - Aglioti, Salvatore M.
PY - 2015/7/8
Y1 - 2015/7/8
N2 - Successful motor interactions require agents to anticipate what a partner is doing in order to predictively adjust their own movements. Although the neural underpinnings of the ability to predict others € action goals have been well explored during passive action observation, no study has yet clarified any critical neural substrate supporting interpersonal coordination during active, non-imitative (complementary) interactions. Here, we combine non-invasive inhibitory brain stimulation (continuous Theta Burst Stimulation) with a novel human-Avatar interaction task to investigate a causal role for higher-order motor cortical regions in supporting the ability to predict and adapt to others € actions. We demonstrate that inhibition of left anterior intraparietal sulcus (aIPS), but not ventral premotor cortex, selectively impaired individuals € performance during complementary interactions. Thus, in addition to coding observed and executed action goals, aIPS is crucial in coding € shared goals €, that is, integrating predictions about one € s and others € complementary actions.
AB - Successful motor interactions require agents to anticipate what a partner is doing in order to predictively adjust their own movements. Although the neural underpinnings of the ability to predict others € action goals have been well explored during passive action observation, no study has yet clarified any critical neural substrate supporting interpersonal coordination during active, non-imitative (complementary) interactions. Here, we combine non-invasive inhibitory brain stimulation (continuous Theta Burst Stimulation) with a novel human-Avatar interaction task to investigate a causal role for higher-order motor cortical regions in supporting the ability to predict and adapt to others € actions. We demonstrate that inhibition of left anterior intraparietal sulcus (aIPS), but not ventral premotor cortex, selectively impaired individuals € performance during complementary interactions. Thus, in addition to coding observed and executed action goals, aIPS is crucial in coding € shared goals €, that is, integrating predictions about one € s and others € complementary actions.
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U2 - 10.1038/ncomms8544
DO - 10.1038/ncomms8544
M3 - Article
AN - SCOPUS:84942033722
VL - 6
JO - Nature Communications
JF - Nature Communications
SN - 2041-1723
M1 - 7544
ER -