Cavitating pulmonary nodules growing in a favourable medium

Cristiano Carbonelli, Francesca Prati, Edoardo Carretto, Alberto Cavazza, Lucia Spaggiari, Giacomo Magnani

Research output: Contribution to journalArticle

Abstract

Pulmonary involvement due to Nocardia is generally associated with cell-mediated immunosuppressive conditions and risk factors like HIV infection, lymphoproliferative diseases, diabetes and steroid therapy. Pulmonary alveolar proteinosis (PAP) is a well-known risk factor for Nocardia infection and is usually easily detectable on a high-resolution CT scan as ground-glass opacities with geographical distribution, crazy paving pattern and varying amounts of pulmonary consolidation. Pulmonary nocardiosis should be considered in apparently immunocompetent patients who present with PAP and a suspected opportunistic infection. We report a case of pulmonary nocardiosis occurring in a patient with radiologically inapparent PAP. The serendipitous finding of PAP on transbronchial biopsy further increased the likelihood of a Nocardia infection, subsequently confirmed by a surgical biopsy.

Original languageEnglish
Pages (from-to)1078-1083
Number of pages6
JournalThorax
Volume68
Issue number11
DOIs
Publication statusPublished - Nov 2013

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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