CD30/CD30 ligand and CD40/CD40 ligand in malignant lymphoid disorders

A. Younes, A. Carbone

Research output: Contribution to journalArticle

Abstract

CD30 and CD40 are members of the tumor necrosis factor (TNF) receptor family. These two receptors have pleiotropic biologic functions including induction of apoptosis and enhancing cell survival. This review will discuss the pattern of expression of these receptors in malignant lymphoid disorders and their prospective ligands. Understanding issues related to these two ligands and their receptors in lymphoid malignancies may help to improve the classification of these diseases and could open the doors for new treatment strategies.

Original languageEnglish
Pages (from-to)135-143
Number of pages9
JournalInternational Journal of Biological Markers
Volume14
Issue number3
Publication statusPublished - Jul 1999

Keywords

  • EBV
  • Hodgkin's disease
  • LMP
  • Lymphoma
  • Reed-Sternberg cells
  • TNF

ASJC Scopus subject areas

  • Immunology
  • Biochemistry

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