Abstract
Women affected by polycystic ovary syndrome (PCOS) have an increased risk of cardiovascular disease. We demonstrated that women with PCOS showed an expansion of CD4+CD28null T cells, an aggressive population of T lymphocytes that has been recently associated with recurrent coronary instability and type 2 diabetes mellitus. This sheds new light on possible mechanisms responsible for the higher rate of cardiovascular disease among women with PCOS.
Original language | English |
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Pages (from-to) | 2651-2654 |
Number of pages | 4 |
Journal | Fertility and Sterility |
Volume | 95 |
Issue number | 8 |
DOIs | |
Publication status | Published - Jun 30 2011 |
Keywords
- Hyperinsulinemia
- inflammation
- polycystic ovary syndrome
- T lymphocytes
ASJC Scopus subject areas
- Obstetrics and Gynaecology
- Reproductive Medicine