CD5 positive B lymphocytes in seronegative juvenile arthritis

A. Martini, M. Massa, F. De Benedetti, S. Viola, G. Neirotti, R. G. Burgio

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

We investigated the levels of circulating CD5+ B cells in 43 patients with seronegative, HLA-B27 negative juvenile arthritis, 7 patients with juvenile dermatomyositis (DM) and 10 children with systemic lupus erythematosus (SLE). We found that CD5+ B cell levels were high in juvenile arthritis (p <0.01), normal in juvenile DM and decreased in SLE (p <0.01) compared to 33 age matched controls. In juvenile arthritis, the increase of CD5+ B cells appeared to be independent of disease activity and was present in all the onset types except in a subset of patients with late onset pauciarthritis.

Original languageEnglish
Pages (from-to)932-935
Number of pages4
JournalJournal of Rheumatology
Volume17
Issue number7
Publication statusPublished - 1990

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Juvenile Arthritis
B-Lymphocytes
Systemic Lupus Erythematosus
HLA-B27 Antigen
Juvenile dermatomyositis

Keywords

  • CD5+ B lymphocytes
  • juvenile arthritis

ASJC Scopus subject areas

  • Immunology
  • Rheumatology

Cite this

CD5 positive B lymphocytes in seronegative juvenile arthritis. / Martini, A.; Massa, M.; De Benedetti, F.; Viola, S.; Neirotti, G.; Burgio, R. G.

In: Journal of Rheumatology, Vol. 17, No. 7, 1990, p. 932-935.

Research output: Contribution to journalArticle

Martini, A. ; Massa, M. ; De Benedetti, F. ; Viola, S. ; Neirotti, G. ; Burgio, R. G. / CD5 positive B lymphocytes in seronegative juvenile arthritis. In: Journal of Rheumatology. 1990 ; Vol. 17, No. 7. pp. 932-935.
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