CD64 expression on monocytes in children with adenoid hypertrophy

Fabio Pagella, Mara De Amici, Elina Matti, Alessandro Pusateri, Marco Benazzo, Giorgio Ciprandi

Research output: Contribution to journalArticle

Abstract

Objective: Adenoids with obstructive hypertrophy (AH) are considered to be one of the most ancient and common problems in Paediatrics. This study aimed at investigating the expression of CD 64 on monocytes in children who had to undergo adenoidectomy. Methods: Therefore, 66 children (24 females, 42 males, mean age 4.9 years), affected by AH and requiring adenoidectomy (54%) or adenotonsillectomy (46%) were consecutively enrolled into the study. Moreover, 30 healthy children (11 females, 19 males, mean age 11.2 years) were enrolled in this study as controls. CD64 expression on monocytes was measured. Results: Children with severe AH had higher CD64 values than children with AH size 3 and controls. Conclusions: This preliminary study shows that CD64 expression on monocytes may be associated with severe AH, suggesting a more intense immune activation in these subjects.

Original languageEnglish
Pages (from-to)132-137
Number of pages6
JournalAsian Pacific Journal of Allergy and Immunology
Volume31
Issue number2
DOIs
Publication statusPublished - 2013

Keywords

  • Adenoid hypertrophy
  • CD64
  • Monocytes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

Fingerprint Dive into the research topics of 'CD64 expression on monocytes in children with adenoid hypertrophy'. Together they form a unique fingerprint.

  • Cite this