cDNA array technology in melanoma: An overview

Alfonso Baldi, Daniele Santini, Antonio De Luca, Marco G. Paggi

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Genetic aberrations, mostly resulting in changes in gene expression, are critical events in cancer onset and progression. The advent of the cDNA array technology allows the screening and the efficient measurement of expression of thousands genes simultaneously in a wide spectrum of experimental and clinical models. This genomic scale approach is being currently used to obtain global views of human cancer gene expression and to identify genetic markers that might be important for diagnosis, prognosis, and therapy. This review discusses some recent findings obtained by means of cDNA arrays investigating the human melanoma.

Original languageEnglish
Pages (from-to)219-223
Number of pages5
JournalJournal of Cellular Physiology
Volume196
Issue number2
DOIs
Publication statusPublished - Aug 1 2003

Fingerprint

Oligonucleotide Array Sequence Analysis
Gene expression
Melanoma
Complementary DNA
Technology
Gene Expression
Aberrations
Screening
Genes
Neoplasm Genes
Genetic Markers
Theoretical Models
Neoplasms
Therapeutics

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Cell Biology
  • Physiology

Cite this

cDNA array technology in melanoma : An overview. / Baldi, Alfonso; Santini, Daniele; De Luca, Antonio; Paggi, Marco G.

In: Journal of Cellular Physiology, Vol. 196, No. 2, 01.08.2003, p. 219-223.

Research output: Contribution to journalArticle

Baldi, Alfonso ; Santini, Daniele ; De Luca, Antonio ; Paggi, Marco G. / cDNA array technology in melanoma : An overview. In: Journal of Cellular Physiology. 2003 ; Vol. 196, No. 2. pp. 219-223.
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