cDNA array technology in melanoma: An overview

Alfonso Baldi, Daniele Santini, Antonio De Luca, Marco G. Paggi

Research output: Contribution to journalArticlepeer-review

Abstract

Genetic aberrations, mostly resulting in changes in gene expression, are critical events in cancer onset and progression. The advent of the cDNA array technology allows the screening and the efficient measurement of expression of thousands genes simultaneously in a wide spectrum of experimental and clinical models. This genomic scale approach is being currently used to obtain global views of human cancer gene expression and to identify genetic markers that might be important for diagnosis, prognosis, and therapy. This review discusses some recent findings obtained by means of cDNA arrays investigating the human melanoma.

Original languageEnglish
Pages (from-to)219-223
Number of pages5
JournalJournal of Cellular Physiology
Volume196
Issue number2
DOIs
Publication statusPublished - Aug 1 2003

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Cell Biology
  • Physiology

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