cDNA Cloning of Three New Homeobox-Containing Genes of the Anf Class from Human, Chicken, and Newt

O. V. Kazanskaya; G. V. Ermakova; M. Pannese; E. Boncinelli; A. G. Zaraisky

cDNA Cloning of Three New Homeobox-Containing Genes of the Anf Class from Human, Chicken, and Newt

O. V. Kazanskaya, G. V. Ermakova, M. Pannese, E. Boncinelli, A. G. Zaraisky

IRCCS Ospedale San Raffaele

Research output: Contribution to journal › Article › peer-review

Abstract

On the basis of the analysis of cDNA of three new homeobox-containing genes from human, chicken and newt, a new class of homebox genes Anf is characterized homologous to the Xanf-1 gene from Xenopus laevis, earlier cloned by us. These genes may be largely involved in the specification of embryonic subdivisions in the forebrain region of the embryo. The homeodomains of the proteins encoded by these genes differ greatly in the primary structure from all previously described homeobox genes. The high variability of the homeodomain sequences of the proteins of this class imply their rapid evolution.

Original language	English
Pages (from-to)	192-193
Number of pages	2
Journal	Bioorganicheskaya Khimiya
Volume	24
Issue number	3
Publication status	Published - Mar 1998

Keywords

Cloning
Forebrain
Homeobox-containing genes
PCR

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)
Organic Chemistry

Cite this

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title = "cDNA Cloning of Three New Homeobox-Containing Genes of the Anf Class from Human, Chicken, and Newt",

abstract = "On the basis of the analysis of cDNA of three new homeobox-containing genes from human, chicken and newt, a new class of homebox genes Anf is characterized homologous to the Xanf-1 gene from Xenopus laevis, earlier cloned by us. These genes may be largely involved in the specification of embryonic subdivisions in the forebrain region of the embryo. The homeodomains of the proteins encoded by these genes differ greatly in the primary structure from all previously described homeobox genes. The high variability of the homeodomain sequences of the proteins of this class imply their rapid evolution.",

keywords = "Cloning, Forebrain, Homeobox-containing genes, PCR",

author = "Kazanskaya, {O. V.} and Ermakova, {G. V.} and M. Pannese and E. Boncinelli and Zaraisky, {A. G.}",

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T1 - cDNA Cloning of Three New Homeobox-Containing Genes of the Anf Class from Human, Chicken, and Newt

AU - Kazanskaya, O. V.

AU - Ermakova, G. V.

AU - Pannese, M.

AU - Boncinelli, E.

AU - Zaraisky, A. G.

PY - 1998/3

Y1 - 1998/3

N2 - On the basis of the analysis of cDNA of three new homeobox-containing genes from human, chicken and newt, a new class of homebox genes Anf is characterized homologous to the Xanf-1 gene from Xenopus laevis, earlier cloned by us. These genes may be largely involved in the specification of embryonic subdivisions in the forebrain region of the embryo. The homeodomains of the proteins encoded by these genes differ greatly in the primary structure from all previously described homeobox genes. The high variability of the homeodomain sequences of the proteins of this class imply their rapid evolution.

AB - On the basis of the analysis of cDNA of three new homeobox-containing genes from human, chicken and newt, a new class of homebox genes Anf is characterized homologous to the Xanf-1 gene from Xenopus laevis, earlier cloned by us. These genes may be largely involved in the specification of embryonic subdivisions in the forebrain region of the embryo. The homeodomains of the proteins encoded by these genes differ greatly in the primary structure from all previously described homeobox genes. The high variability of the homeodomain sequences of the proteins of this class imply their rapid evolution.

KW - Cloning

KW - Forebrain

KW - Homeobox-containing genes

KW - PCR

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cDNA Cloning of Three New Homeobox-Containing Genes of the Anf Class from Human, Chicken, and Newt

Abstract

Keywords

ASJC Scopus subject areas

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