Cefotetan versus piperacillin in the prophylaxis of abdominal and vaginal hysterectomy: A prospective randomized study

M. Regallo; S. Scalambrino; L. Negri; F. Landoni; C. Mangioni

Cefotetan versus piperacillin in the prophylaxis of abdominal and vaginal hysterectomy: A prospective randomized study

M. Regallo, S. Scalambrino, L. Negri, F. Landoni, C. Mangioni

Istituto Europeo di Oncologia

Research output: Contribution to journal › Article › peer-review

Abstract

A prospective randomized study was carried out on a total of 686 patients who underwent vaginal or abdominal hysterectomy. Of these, 338 were given prophylactic cefotetan (2 g) and 348 piperacillin (2 g). Both drugs were administered as i.v. bolus 30 min before operation. Findings confirm the higher risk of infection with abdominal hysterectomy and the advantages of the long half-life cephalosporin, cefotetan.

Original language	English
Pages (from-to)	315-320
Number of pages	6
Journal	Drugs under Experimental and Clinical Research
Volume	15
Issue number	6-7
Publication status	Published - 1989

ASJC Scopus subject areas

Molecular Medicine
Pharmacology (medical)
Drug Discovery
Pharmacology

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abstract = "A prospective randomized study was carried out on a total of 686 patients who underwent vaginal or abdominal hysterectomy. Of these, 338 were given prophylactic cefotetan (2 g) and 348 piperacillin (2 g). Both drugs were administered as i.v. bolus 30 min before operation. Findings confirm the higher risk of infection with abdominal hysterectomy and the advantages of the long half-life cephalosporin, cefotetan.",

author = "M. Regallo and S. Scalambrino and L. Negri and F. Landoni and C. Mangioni",

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AU - Negri, L.

AU - Landoni, F.

AU - Mangioni, C.

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