Cefotetan versus piperacillin in the prophylaxis of abdominal and vaginal hysterectomy: A prospective randomized study

M. Regallo, S. Scalambrino, L. Negri, F. Landoni, C. Mangioni

Research output: Contribution to journalArticlepeer-review

Abstract

A prospective randomized study was carried out on a total of 686 patients who underwent vaginal or abdominal hysterectomy. Of these, 338 were given prophylactic cefotetan (2 g) and 348 piperacillin (2 g). Both drugs were administered as i.v. bolus 30 min before operation. Findings confirm the higher risk of infection with abdominal hysterectomy and the advantages of the long half-life cephalosporin, cefotetan.

Original languageEnglish
Pages (from-to)315-320
Number of pages6
JournalDrugs under Experimental and Clinical Research
Volume15
Issue number6-7
Publication statusPublished - 1989

ASJC Scopus subject areas

  • Molecular Medicine
  • Pharmacology (medical)
  • Drug Discovery
  • Pharmacology

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