Celiac disease and endocrine autoimmune disorders in children: An update

Antonella Diamanti, Teresa Capriati, Carla Bizzarri, Fabio Panetta, Francesca Ferretti, Monica Ancinelli, Francesca Romano, Mattia Locatelli

Research output: Contribution to journalArticle

Abstract

Celiac disease (CD) is a life-long inflammatory condition of the gut that occurs in genetically susceptible individuals. Several autoimmune diseases (AI) are associated with CD. To date, no conclusive evidence is available that proves if the relationship between CD and AI is mediated by gluten exposure, or if CD and AI could co-occur due to other causes, in particular the loss of the intestinal barrier function and the common genetic background. Furthermore, it is not clear yet if CD needs a regular screening program for AI. This review will cover the key studies on both the pathogenetic and clinical evidence explaining this association. We will review the reports including patients aged

Original languageEnglish
Pages (from-to)1289-1301
Number of pages13
JournalExpert Review of Clinical Immunology
Volume9
Issue number12
DOIs
Publication statusPublished - 2013

Keywords

  • Addison's disease
  • Adolescent
  • Autoimmune diseases
  • Celiac disease
  • Child
  • Thyroid autoimmunity
  • Type 1 diabetes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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