Celiac disease-associated autoimmune hepatitis in childhood: Long-term response to treatment

Silvia Nastasio, Marco Sciveres, Silvia Riva, Irene P. Filippeschi, Pietro Vajro, Giuseppe Maggiore

Research output: Contribution to journalArticlepeer-review

Abstract

OBJECTIVES:: Celiac disease (CD) is common in patients with autoimmune liver disease (AILD); however, the long-term response to treatment of patients with AILDs coexistent with CD has not been explored in detail. The aim of the present study was to analyze the features and the long-term response to immunosuppressive treatment in children with autoimmune hepatitis (AIH) associated with CD. METHODS:: Retrospective and prospective evaluation of patients followed at a single center. RESULTS:: Among 79 patients with AIH, 15 (19%) had CD (9 type 1, 3 type 2, 3 seronegative). In the group of patients with AIH and CD, female sex was significantly more represented than in the group of patients with AIH alone; also, in the former group, diagnosis was made significantly earlier (P 

Original languageEnglish
Pages (from-to)671-674
Number of pages4
JournalJournal of Pediatric Gastroenterology and Nutrition
Volume56
Issue number6
DOIs
Publication statusPublished - Jun 2013

Keywords

  • autoimmune hepatitis
  • celiac disease
  • immunosuppressive treatment

ASJC Scopus subject areas

  • Gastroenterology
  • Pediatrics, Perinatology, and Child Health

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