Abstract
Ten patients (5 males) affected by epilepsy with cerebral calcifications of unknown etiology mainly located in the posterior regions were subjected to a battery of tests including an intestinal biopsy. Our aim was to establish whether or not the patients also suffered from celiac disease. Celiac disease was found in 6 patients. This result and the individual cases reported in the literature suggest that this triad of diseases (celiac disease, posterior cerebral calcifications and epilepsy) are causally related. The same HLA phenotype was found in all 10 patients, i.e., including the cases without celiac disease, suggesting an underlying disorder of the immune system. Our results emphasize that particular attention should be paid to a search for celiac disease in all patients with epilepsy and posterior cerebral calcifications.
| Original language | English |
|---|---|
| Pages (from-to) | 23-29 |
| Number of pages | 7 |
| Journal | Brain and Development |
| Volume | 14 |
| Issue number | 1 |
| Publication status | Published - 1992 |
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Keywords
- Celiac disease
- Epilepsy
- Posterior cerebral calcifications
ASJC Scopus subject areas
- Clinical Neurology
- Pediatrics, Perinatology, and Child Health
- Neurology
Cite this
Celiac disease, posterior cerebral calcifications and epilepsy. / Gobbi, G.; Ambrosetto, P.; Zaniboni, M. G.; Lambertini, A.; Ambrosioni, G.; Tassinari, C. A.
In: Brain and Development, Vol. 14, No. 1, 1992, p. 23-29.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Celiac disease, posterior cerebral calcifications and epilepsy
AU - Gobbi, G.
AU - Ambrosetto, P.
AU - Zaniboni, M. G.
AU - Lambertini, A.
AU - Ambrosioni, G.
AU - Tassinari, C. A.
PY - 1992
Y1 - 1992
N2 - Ten patients (5 males) affected by epilepsy with cerebral calcifications of unknown etiology mainly located in the posterior regions were subjected to a battery of tests including an intestinal biopsy. Our aim was to establish whether or not the patients also suffered from celiac disease. Celiac disease was found in 6 patients. This result and the individual cases reported in the literature suggest that this triad of diseases (celiac disease, posterior cerebral calcifications and epilepsy) are causally related. The same HLA phenotype was found in all 10 patients, i.e., including the cases without celiac disease, suggesting an underlying disorder of the immune system. Our results emphasize that particular attention should be paid to a search for celiac disease in all patients with epilepsy and posterior cerebral calcifications.
AB - Ten patients (5 males) affected by epilepsy with cerebral calcifications of unknown etiology mainly located in the posterior regions were subjected to a battery of tests including an intestinal biopsy. Our aim was to establish whether or not the patients also suffered from celiac disease. Celiac disease was found in 6 patients. This result and the individual cases reported in the literature suggest that this triad of diseases (celiac disease, posterior cerebral calcifications and epilepsy) are causally related. The same HLA phenotype was found in all 10 patients, i.e., including the cases without celiac disease, suggesting an underlying disorder of the immune system. Our results emphasize that particular attention should be paid to a search for celiac disease in all patients with epilepsy and posterior cerebral calcifications.
KW - Celiac disease
KW - Epilepsy
KW - Posterior cerebral calcifications
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M3 - Article
C2 - 1590524
AN - SCOPUS:0026535842
VL - 14
SP - 23
EP - 29
JO - Brain and Development
JF - Brain and Development
SN - 0387-7604
IS - 1
ER -