Cell-based therapies for diabetic complications

Paola Secchiero, Stella Bernardi, Giovanni Maria Severini, Giorgio Zauli

Research output: Contribution to journalArticlepeer-review


In recent years, accumulating experimental evidence supports the notion that diabetic patients may greatly benefit from cell-based therapies, which include the use of adult stem and/or progenitor cells. In particular, mesenchymal stem cells and the circulating pool of endothelial progenitor cells have so far been the most studied populations of cells proposed for the treatment of vascular complications affecting diabetic patients. We review the evidence supporting their use in this setting, the therapeutic benefits that these cells have shown so far as well as the challenges that cell-based therapies in diabetic complications put out.

Original languageEnglish
Article number872504
JournalExperimental Diabetes Research
Publication statusPublished - 2012

ASJC Scopus subject areas

  • Medicine(all)
  • Endocrinology, Diabetes and Metabolism
  • Music


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