Abstract
Mutations in the dystrophin gene cause an X-linked genetic disorder: Duchenne muscular dystrophy (DMD). Stem cell therapy is an attractive method to treat DMD because a small number of cells are required to obtain a therapeutic effect. Here, we discussed about multiple types of myogenic stem cells and their possible use to treat DMD. The identification of a stem cell population providing efficient muscle regeneration is critical for the progression of cell therapy for DMD. We speculated that the most promising possibility for the treatment of DMD is a combination of different approaches, such as gene and stem cell therapy.
Original language | English |
---|---|
Pages (from-to) | 526-534 |
Number of pages | 9 |
Journal | Journal of Cellular Physiology |
Volume | 221 |
Issue number | 3 |
DOIs | |
Publication status | Published - Dec 2009 |
ASJC Scopus subject areas
- Clinical Biochemistry
- Cell Biology
- Physiology