Abstract
Mutations in the dystrophin gene cause an X-linked genetic disorder: Duchenne muscular dystrophy (DMD). Stem cell therapy is an attractive method to treat DMD because a small number of cells are required to obtain a therapeutic effect. Here, we discussed about multiple types of myogenic stem cells and their possible use to treat DMD. The identification of a stem cell population providing efficient muscle regeneration is critical for the progression of cell therapy for DMD. We speculated that the most promising possibility for the treatment of DMD is a combination of different approaches, such as gene and stem cell therapy.
| Original language | English |
|---|---|
| Pages (from-to) | 526-534 |
| Number of pages | 9 |
| Journal | Journal of Cellular Physiology |
| Volume | 221 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - Dec 2009 |
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ASJC Scopus subject areas
- Clinical Biochemistry
- Cell Biology
- Physiology
Cite this
Cell based therapy for duchenne muscular dystrophy. / Farini, Andrea; Razini, Paola; Erratico, Silvia; Torrente, Yvan; Meregalli, Mirella.
In: Journal of Cellular Physiology, Vol. 221, No. 3, 12.2009, p. 526-534.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Cell based therapy for duchenne muscular dystrophy
AU - Farini, Andrea
AU - Razini, Paola
AU - Erratico, Silvia
AU - Torrente, Yvan
AU - Meregalli, Mirella
PY - 2009/12
Y1 - 2009/12
N2 - Mutations in the dystrophin gene cause an X-linked genetic disorder: Duchenne muscular dystrophy (DMD). Stem cell therapy is an attractive method to treat DMD because a small number of cells are required to obtain a therapeutic effect. Here, we discussed about multiple types of myogenic stem cells and their possible use to treat DMD. The identification of a stem cell population providing efficient muscle regeneration is critical for the progression of cell therapy for DMD. We speculated that the most promising possibility for the treatment of DMD is a combination of different approaches, such as gene and stem cell therapy.
AB - Mutations in the dystrophin gene cause an X-linked genetic disorder: Duchenne muscular dystrophy (DMD). Stem cell therapy is an attractive method to treat DMD because a small number of cells are required to obtain a therapeutic effect. Here, we discussed about multiple types of myogenic stem cells and their possible use to treat DMD. The identification of a stem cell population providing efficient muscle regeneration is critical for the progression of cell therapy for DMD. We speculated that the most promising possibility for the treatment of DMD is a combination of different approaches, such as gene and stem cell therapy.
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UR - http://www.scopus.com/inward/citedby.url?scp=70449710932&partnerID=8YFLogxK
U2 - 10.1002/jcp.21895
DO - 10.1002/jcp.21895
M3 - Article
VL - 221
SP - 526
EP - 534
JO - Journal of cellular and comparative physiology
JF - Journal of cellular and comparative physiology
SN - 0021-9541
IS - 3
ER -