Cell kinetic investigations in craniopharyngioma: Preliminary results and considerations

G. Broggi, A. Franzini, L. Cajola, F. Pluchino

Research output: Contribution to journalArticle

Abstract

In vitro determination of 3H-thymidine labeling index (LI%) was carried out in craniopharyngiomas from 16 patients submitted to repeated surgical procedures. This study showed a poor correlation between LI% values and prognosis, but allowed to detect a high LI% variation in the same tumor investigated in serial different times. The spatial distribution of S-phase proliferative cells in squamous epithelium of cystic components suggests a rationale for intracavitary treatment of cystic and mixed craniopharingioma and may help explain its success.

Original languageEnglish
Pages (from-to)21-23
Number of pages3
JournalPediatric Neurosurgery
Volume21
Issue numberSUPPL. 1
Publication statusPublished - 1994

Keywords

  • bleomycin
  • cell kinetics
  • craniopharyngioma

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health

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