In vitro determination of 3H-thymidine labeling index (LI%) was carried out in craniopharyngiomas from 16 patients submitted to repeated surgical procedures. This study showed a poor correlation between LI% values and prognosis, but allowed to detect a high LI% variation in the same tumor investigated in serial different times. The spatial distribution of S-phase proliferative cells in squamous epithelium of cystic components suggests a rationale for intracavitary treatment of cystic and mixed craniopharingioma and may help explain its success.
|Number of pages||3|
|Issue number||SUPPL. 1|
|Publication status||Published - 1994|
- cell kinetics
ASJC Scopus subject areas
- Clinical Neurology
- Pediatrics, Perinatology, and Child Health