Cell kinetics and hormonal features in relation to pathological stage in breast cancer

Dino Amadori; Chiara Bonaguri; Oriana Nanni; Patrizia Gentilini; Nadia Lundi; Wainer Zoli; Angela Riccobon; Antonio Vio; Enrico Magni; Ariele Saragoni

doi:10.1007/BF01975439

Cell kinetics and hormonal features in relation to pathological stage in breast cancer

Dino Amadori, Chiara Bonaguri, Oriana Nanni, Patrizia Gentilini, Nadia Lundi, Wainer Zoli, Angela Riccobon, Antonio Vio, Enrico Magni, Ariele Saragoni

Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori

Research output: Contribution to journal › Article › peer-review

Abstract

Proliferative activity (expressed as³H-thymidine labeling index,³H-TdR LI) was evaluated on a series of 281 primary tumors recruited in two years in 6 different institutions from central Italy.³H-TdR LI proved to be low in intraductal, or well and moderately differentiated, or hormone receptor positive tumors. Conversely, no relation was observed between³H-TdR LI and menopause, tumor size, or lymph node involvement. An inverse relation was observed between³H-TdR LI and hormone receptor content. Specific patterns of³H-TdR LI value and ER content association were observed as a function of menopause, lymph nodal status, and degree of lymph nodal involvement.

Original language	English
Pages (from-to)	19-25
Number of pages	7
Journal	Breast Cancer Research and Treatment
Volume	18
Issue number	1
DOIs	https://doi.org/10.1007/BF01975439
Publication status	Published - Mar 1991

Keywords

estrogen receptors
progesterone receptors
prognostic factors
proliferative rate
thymidine labeling index

ASJC Scopus subject areas

Oncology
Cancer Research

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10.1007/BF01975439

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Cell kinetics and hormonal features in relation to pathological stage in breast cancer. / Amadori, Dino; Bonaguri, Chiara; Nanni, Oriana; Gentilini, Patrizia; Lundi, Nadia; Zoli, Wainer; Riccobon, Angela; Vio, Antonio; Magni, Enrico; Saragoni, Ariele.

In: Breast Cancer Research and Treatment, Vol. 18, No. 1, 03.1991, p. 19-25.

Research output: Contribution to journal › Article › peer-review

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AU - Lundi, Nadia

AU - Zoli, Wainer

AU - Riccobon, Angela

AU - Vio, Antonio

AU - Magni, Enrico

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