Abstract
Proliferative activity (expressed as3H-thymidine labeling index,3H-TdR LI) was evaluated on a series of 281 primary tumors recruited in two years in 6 different institutions from central Italy.3H-TdR LI proved to be low in intraductal, or well and moderately differentiated, or hormone receptor positive tumors. Conversely, no relation was observed between3H-TdR LI and menopause, tumor size, or lymph node involvement. An inverse relation was observed between3H-TdR LI and hormone receptor content. Specific patterns of3H-TdR LI value and ER content association were observed as a function of menopause, lymph nodal status, and degree of lymph nodal involvement.
Original language | English |
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Pages (from-to) | 19-25 |
Number of pages | 7 |
Journal | Breast Cancer Research and Treatment |
Volume | 18 |
Issue number | 1 |
DOIs | |
Publication status | Published - Mar 1991 |
Keywords
- estrogen receptors
- progesterone receptors
- prognostic factors
- proliferative rate
- thymidine labeling index
ASJC Scopus subject areas
- Oncology
- Cancer Research