Cell mediated immune reactions to specific and aspecific antigens in colon carcinoma

E. Sega, M. Mottolese, P. Cordiali Fei

Research output: Contribution to journalArticle

Abstract

Cell mediated immune reactions to specific colon carcinoma soluble antigens (SMA) in autologous system were studied in 16 patients operated on for colon carcinoma and related to aspecific immunologic tests and short term prognosis. Five patients showed a positive delayed hypersensitivity (D.H.) reaction to SMA in the early postoperative period, and two switched on from negative to positive response some months after surgery. So a total of seven positive D.H. to SMA was found, while only in one case was a lymphoblastic response to SMA reported. While the prognostic value of lymphoblastic response to phytohaemagglutinin both as mean and single values was confirmed the full significance of D.H. reactions to SMA requires a longer follow up.

Original languageEnglish
Pages (from-to)43-50
Number of pages8
JournalSurgery in Italy
Volume6
Issue number1
Publication statusPublished - 1976

ASJC Scopus subject areas

  • Medicine(all)

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