Cellular atypia in vulvar dystrophies

L. Micheletti, G. Borgno, M. Barbero, M. Preti, L. Cavanna, C. Benedetto, B. Ghiringhello

Research output: Contribution to journalArticlepeer-review


We studied the frequency and distribution of cellular atypia in 448 cases of vulvar dystrophy. The total frequency was 9.4%. Atypia was found almost exclusively in hyperplastic areas. Epithelial changes suggestive of human papillomavirus infection were found in 14.2% of the atypical dystrophies. During the follow-up of 78 patients with typical dystrophy, mild atypia developed in three cases, but with the continuation of medical treatment it disappeared in two cases. Eleven cases of atypical dystrophy were followed for 3-48 months; three patients with severe atypia underwent surgical treatment, and eight with mild atypia underwent medical treatment. Among the last patients, six showed regression and two, progression of the atypia.

Original languageEnglish
Pages (from-to)539-541
Number of pages3
JournalJournal of Reproductive Medicine for the Obstetrician and Gynecologist
Issue number6
Publication statusPublished - 1988

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Reproductive Medicine


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