Cellular immunity in cancer patients against embryonal cells

G. Fossati, S. Canevari, G. Della Porta

Research output: Contribution to journalArticlepeer-review

Abstract

A study was made by in vitro cytotoxic microassay of the cellular immune reaction of patients with different types of tumor against cells from 2 human embryos and 2 fetuses. Peripheral blood lymphocytes from 13 to 19 patients with malignant tumor and 1 of 6 patients with benign tumor showed a killing effect on 1 to 2 mth old embryo cells, whereas no cytotoxicity was demonstrated against 4 to 5 mth old fetal cells and adult skin fibroblasts. These data suggest that patients with malignant tumor are sensitized against antigen(s) in embryo cells.

Original languageEnglish
Pages (from-to)667-669
Number of pages3
JournalJournal of the National Cancer Institute
Volume51
Issue number2
Publication statusPublished - 1973

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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