Central Nervous System Complications in Children Receiving Chemotherapy or Hematopoietic Stem Cell Transplantation

Duccio Maria Cordelli, Riccardo Masetti, Daniele Zama, Francesco Toni, Ilaria Castelli, Emilia Ricci, Emilio Franzoni, Andrea Pession

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Therapy-related neurotoxicity greatly affects possibility of survival and quality of life of pediatric patients treated for cancer. Central nervous system (CNS) involvement is heterogeneous, varying from very mild and transient symptoms to extremely severe and debilitating, or even lethal syndromes. In this review, we will discuss the broad scenario of CNS complications and toxicities occurring during the treatment of pediatric patients receiving both chemotherapies and hematopoietic stem cell transplantation. Different types of complications are reviewed ranging from therapy related to cerebrovascular with a specific focus on neuroradiologic and clinical features.
Original languageEnglish
Article number105
Pages (from-to)1-15
JournalFrontiers in Pediatrics
Volume5
DOIs
Publication statusPublished - May 15 2017

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Hematopoietic Stem Cell Transplantation
Central Nervous System
Drug Therapy
Pediatrics
Therapeutics
Quality of Life
Survival
Neoplasms

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Central Nervous System Complications in Children Receiving Chemotherapy or Hematopoietic Stem Cell Transplantation. / Cordelli, Duccio Maria; Masetti, Riccardo; Zama, Daniele; Toni, Francesco; Castelli, Ilaria; Ricci, Emilia; Franzoni, Emilio; Pession, Andrea.

In: Frontiers in Pediatrics, Vol. 5, 105, 15.05.2017, p. 1-15.

Research output: Contribution to journalArticle

Cordelli, Duccio Maria ; Masetti, Riccardo ; Zama, Daniele ; Toni, Francesco ; Castelli, Ilaria ; Ricci, Emilia ; Franzoni, Emilio ; Pession, Andrea. / Central Nervous System Complications in Children Receiving Chemotherapy or Hematopoietic Stem Cell Transplantation. In: Frontiers in Pediatrics. 2017 ; Vol. 5. pp. 1-15.
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