Abstract
Extranodal marginal zone B-cell lymphomas are linked to bacterial infections that vary according to the anatomical site. The occurrence of these lymphomas in the central nervous system is a very rare event, and the identification of specific bacteria in this setting has not been previously addressed. Herein, we report for the first time a case of primary central nervous system marginal zone B-cell lymphoma involving the choroid plexus associated with Chlamydophila psittaci infection. No concomitant ocular involvement was detected. C psittaci was identified with 3 independent methods, and through immunohistochemistry, it was visualized in the cytoplasm of monocytes/macrophages present within lymphomatous tissues. This observation points toward the opportunity to investigate the prevalence of C psittaci infection in central nervous system lymphomas, particularly in those with low-grade histologic features.
Original language | English |
---|---|
Pages (from-to) | 738-742 |
Number of pages | 5 |
Journal | Human Pathology |
Volume | 42 |
Issue number | 5 |
DOIs | |
Publication status | Published - May 2011 |
Keywords
- Central nervous system
- Chlamydia
- Infection
- Lymphoma
- Marginal zone
ASJC Scopus subject areas
- Pathology and Forensic Medicine