Centrocytic-like lymphoma associated with localized amyloidosis of the large intestine

R. Ranaldi, G. Goteri, A. Santinelli, B. Rezai, I. Bearzi, S. Pileri, S. Poggi

Research output: Contribution to journalArticle

Abstract

A case of low-grade centrocytic-like (CCL) B-cell lymphoma involving the large intestine, the regional lymph nodes and the spleen is reported. In the large intestine the lymphomatous infiltrate was restricted to sites of intense antigenic stimulation (diverticula, appendix, ileo-caecal valve) and was associated with marked plasma cell differentiation and massive amyloid deposits. The immunophenotype was CD20, CD21, CD45RA/MB1/MT2, CD68, CD45 related/Ki-B3 and HLA-DR positive, and MB2, DBA.44 reactive regarding the CCL cell lymphoma subpopulation; and IgG-λ positive regarding its plasma cell fraction.

Original languageEnglish
Pages (from-to)327-330
Number of pages4
JournalVirchows Archiv
Volume425
Issue number3
DOIs
Publication statusPublished - 2004

Keywords

  • Centrocytic-like lymphoma
  • Large intestine
  • Localized amyloidosis

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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    Ranaldi, R., Goteri, G., Santinelli, A., Rezai, B., Bearzi, I., Pileri, S., & Poggi, S. (2004). Centrocytic-like lymphoma associated with localized amyloidosis of the large intestine. Virchows Archiv, 425(3), 327-330. https://doi.org/10.1007/BF00196157