TY - JOUR
T1 - Cerebellar hypoplasia, continuous spike-waves during sleep, and neuropsychological and behavioral disorders
AU - Parmeggiani, Antonia
AU - Posar, Annio
AU - Scaduto, Cristina Maria
PY - 2008
Y1 - 2008
N2 - We describe 3 patients with different degrees of cerebellar hypoplasia and continuous spike-waves during sleep: the more extensive the cerebellar hypoplasia, the more compromised the neuropsychological abilities and behavior. Cerebellar hypoplasia is a risk factor for epilepsy and/or neuropsychological and psychiatric disorders. Epilepsy is also strongly associated with familial antecedents for seizures, as previously reported. The cerebellum is implicated in controlling epileptic seizures and in regulating motor, cognitive, and emotional functions with a topographic organization. The association between cerebellar hypoplasia and continuous spike-waves during sleep has never been reported. We suggest that continuous spike-waves during sleep may further compromise neuropsychological and behavioral features that are associated with cerebellar hypoplasia.
AB - We describe 3 patients with different degrees of cerebellar hypoplasia and continuous spike-waves during sleep: the more extensive the cerebellar hypoplasia, the more compromised the neuropsychological abilities and behavior. Cerebellar hypoplasia is a risk factor for epilepsy and/or neuropsychological and psychiatric disorders. Epilepsy is also strongly associated with familial antecedents for seizures, as previously reported. The cerebellum is implicated in controlling epileptic seizures and in regulating motor, cognitive, and emotional functions with a topographic organization. The association between cerebellar hypoplasia and continuous spike-waves during sleep has never been reported. We suggest that continuous spike-waves during sleep may further compromise neuropsychological and behavioral features that are associated with cerebellar hypoplasia.
KW - Cerebellum
KW - Cognition
KW - Epilepsy
UR - http://www.scopus.com/inward/record.url?scp=57749209831&partnerID=8YFLogxK
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U2 - 10.1177/0883073808319077
DO - 10.1177/0883073808319077
M3 - Article
C2 - 19073855
AN - SCOPUS:57749209831
VL - 23
SP - 1472
EP - 1476
JO - Journal of Child Neurology
JF - Journal of Child Neurology
SN - 0883-0738
IS - 12
ER -