Cerebellar medullomyoblastoma with melanotic tubular structures

Paolo Nozza, Claudia Milanaccio, Gianluca Piatelli, Andrea Rossi, Alessandro Raso, Armando Cama, Maria L. Garré, Torsten Pietsch

Research output: Contribution to journalArticlepeer-review


This report describes a midline cerebellar primitive neuroectodermal tumor with muscular differentiation, that is, medullomyoblastoma with melanotic tubular structures, which developed in the cerebellar vermis in a 23-month-old male. Rhabdomyoblastic differentiation consisted both of striated muscle fibers and undifferentiated cells showing immunoreactivity for desmin and myogenic transcription factors. The presence of melanotic epithelial structures raised the issue of a teratomatous tumor. This case demonstrates the occurrence of this very rare tumor in early childhood as well as the utility of a careful search for the presence of myogenic and/or melanotic features in medulloblastomas.

Original languageEnglish
Pages (from-to)183-185
Number of pages3
JournalPediatric Blood and Cancer
Issue number1
Publication statusPublished - Jan 2008


  • Brain tumors
  • Medullomyoblastoma
  • Pigmented medulloblastoma

ASJC Scopus subject areas

  • Cancer Research
  • Pediatrics, Perinatology, and Child Health
  • Hematology


Dive into the research topics of 'Cerebellar medullomyoblastoma with melanotic tubular structures'. Together they form a unique fingerprint.

Cite this